Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol AIDA contributors: KTN/npt - updated : 29/12/2008
HGNC name axin interactor, dorsalization associated
HGNC id 25761
Location 1q41      Physical location : 222.841.356 - 222.885.864
Synonym name
  • chromosome 1 open reading frame 80
  • axin interaction partner and dorsalization antagonist
  • Synonym symbol(s) C1orf80, FLJ12806, FLJ32421, RP11-378J18.7
    DNA
    TYPE functioning gene
    STRUCTURE 44.51 kb     10 Exon(s)
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 3020 34.9 306 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularvessel   highly
    Endocrineadrenal gland   moderately
     neuroendocrinepituitary  moderately
     parathyroid   moderately
     thyroid   moderately
    Reproductivemale systemprostate  predominantly
     male systemtestis  moderately
    Respiratoryrespiratory tractlarynx  moderately
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to dog AIDA (98.7 pc)
    homolog to chimpanzee AIDA (100 pc)
    homolog to cow AIDA (99.7 pc)
    homolog to murine Aida (98 pc)
    homolog to chicken AIDA (95.1 pc)
    Homologene
    FAMILY
  • AIDA family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • actin as a ventralizing factor during embryogenesis
  • inhibiting axin-mediated JNK activation by binding axin and disrupting axin homodimerization
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text
  • dorsal/ventral pattern formation
  • PATHWAY
    metabolism
    signaling signal transduction
  • negative regulation of JNK cascade
  • a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with AXIN1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS