motifs/domains
| binding motifs for the gamma-ear domain GAE of clathrin adaptor protein 1 (AP-1) |
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a second, atypical clathrin binding site, YQW, colocalizing with AP-1 and enriched in clathrin-coated vesicles |
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eight GAE |
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a core tetrapeptide motif PsiG(P/D/E)(Psi/L/M) (where Psi is an aromatic residue), responsible for the interactions of accessory proteins with GAE domains |
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two WXXF-acidic motifs mediating binding to the alpha-ear AP-2 |
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three FXXFXXF/L motifs mediating binding to the alpha- and beta2-ear |