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FLASH GENE
Symbol ADSS2 contributors: mct - updated : 07-04-2021
HGNC name adenylosuccinate synthase 2
HGNC id 292
Location 1q44      Physical location : -
Synonym name
  • adenylosuccinate synthetase (Ade(-)H-complementing)
  • adenylosuccinate synthetase, liver isozyme
  • epididymis secretory sperm binding protein
  • Synonym symbol(s) ADEH, MGC20404, ADSS, ADSS 2
    EC.number 6.3.4.4
    DNA
    TYPE functioning gene
    STRUCTURE 43.57 kb     13 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    13 splicing 2697 - 453 - 1992 1592113
    13 - 2555 - 456 - 1992 1592113
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveesophagus   highly
    Endocrineparathyroid   highly
    Reproductivemale systemtestis  highly
    Respiratoryrespiratory tracttrachea  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    mono polymer homomer , dimer
    HOMOLOGY
    Homologene
    FAMILY adenylosuccinate synthetase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • adenylosuccinate synthase, purine nucleotide cycle
  • plays an important role in the de novo pathway of purine nucleotide biosynthesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    binds 1 magnesium ion per subunit
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS