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FLASH GENE
Symbol ADNP2 contributors: mct - updated : 16-10-2015
HGNC name ADNP homeobox 2
HGNC id 23803
Location 18q23      Physical location : 77.866.914 - 77.898.226
Synonym name
  • KIAA0863 protein
  • zinc finger protein 508
  • Synonym symbol(s) KIAA0863, ZNF508
    DNA
    TYPE functioning gene
    STRUCTURE 31.32 kb     4 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 5401 122.8 1131 - 2008 1817947
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Nervousoligodendrocyte Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo
    Text photoreceptor cells in development
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , dimer
    HOMOLOGY
    intraspecies homolog to ADNP
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text soma and axons of photoreceptor cells of compound eyes and ocelli.
    basic FUNCTION
  • may be functioning as a calcium-sequestering "sponge" to regulate the amount of free cytoplasmic calcium
  • may have an important function in brain by playing a role in cellular survival pathways
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • imbalance in ADNP/ADNP2 expression in the brain may impact disease progression in schizophrenia
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS