Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ADM2 contributors: - updated : 14-09-2005
HGNC name adrenomedullin 2
HGNC id 28898
Location 22q13.33      Physical location : 50.920.011 - 50.924.864
Synonym name intermedin
Synonym symbol(s) AM2, FLJ21135
DNA
TYPE functioning gene
STRUCTURE 5.00 kb     2 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestine    
Endocrineneuroendocrinepituitary   
Respiratoryrespiratory tractlarynx   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an N-terminal signal peptide
  • C-terminal half with a dibasic cleavage site
  • a 47-amino acid mature peptide hormone sequence
  • an alpha-amidation donor glycine at the C terminus
  • HOMOLOGY
    Homologene
    FAMILY calcitonin - related peptide hormones family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in the regulation of peripheral tissues by calcitonin receptor-like receptor
  • may play pivotal roles in cardiovascular and body fluid regulation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with CRLR/RAMP receptor complex (required for intermedin signaling)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS