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FLASH GENE
Symbol ADH6 contributors: mct - updated : 14-06-2006
HGNC name alcohol dehydrogenase 6 (class V)
HGNC id 255
Location 4q23      Physical location : 100.123.794 - 100.140.403
Synonym name aldehyde reductase
Synonym symbol(s) ADH5
EC.number 1.1.1.1
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text cluster of seven genes spanning approximately 365 kb on chromosome 4q23 (Pochareddy 2010)
STRUCTURE 16.61 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter (TATA box)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 1400 39 368 - -
9 - 2803 39.7 375 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
 stomach    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text liver
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • gluco-corticoid response element at the N terminus
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • zinc-containing alcohol dehydrogenase family
  • class-V subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • alcohol dehydrogenase (class V), zinc dependent, metabolizing a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism other
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS