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FLASH GENE
Symbol ADCY7 contributors: - updated : 07-01-2006
HGNC name adenylate cyclase 7
HGNC id 238
Location 16q12-q13      Physical location : 50.321.822 - 50.352.043
Synonym name
  • ATP pyrophosphate-lyase
  • Synonym symbol(s) KIAA0037
    EC.number 4.6.1.1
    DNA
    TYPE functioning gene
    STRUCTURE 29.00 kb     25 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node   highly
     thymus   highly
    Reproductivefemale systemplacenta  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • twelve transmembrane domains (12TM)
  • 2 guanylate cyclase domains
  • HOMOLOGY
    Homologene
    FAMILY adenylyl cyclase class-4/guanylyl cyclase enzyme family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION adenylate cyclase catalysing the formation of cyclic AMP from ATP and inhibitable by calcium
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    binds 2 magnesium ions per subunit
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS