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FLASH GENE
Symbol ADCY7 contributors: - updated : 07-01-2006
HGNC name adenylate cyclase 7
HGNC id 238
Location 16q12-q13      Physical location : 50.321.822 - 50.352.043
Synonym name
  • ATP pyrophosphate-lyase
  • Synonym symbol(s) KIAA0037
    EC.number 4.6.1.1
    DNA
    TYPE functioning gene
    STRUCTURE 29.00 kb     25 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    Physical map
    ABCC11 16q11-q12 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 LONP 16q12.1 peroxisomal lon protease SIAH1 16q12 seven in absentia homolog 1 (Drosophila) LOC255896 16q12.1 similar to molybdenum cofactor synthesis-step 1 protein isoform 2 FLJ31821 16q12.1 hypothetical protein FLJ31821 N4BP1 16q12.1 hypothetical protein FLJ31821 LOC388273 16 LOC388273 CBLN1 16q11.2-q12.2 cerebellin 1 precursor MGC33367 16q12.1 hypothetical protein MGC32905 OAZ 16q12 hypothetical protein MGC32905 ADAM3B 16q12.1 a disintegrin and metalloproteinase domain 3b (cyritestin 2) MRPS21P7 16q12.1 mitochondrial ribosomal protein S21 pseudogene 7 MRPS21P8 16q12.1 mitochondrial ribosomal protein S21 pseudogene 8 FLJ38101 16q12.1 hypothetical protein FLJ38101 FLJ20718 16q12.1 hypothetical protein FLJ20718 LOC390729 16 similar to 60S ribosomal protein L10 (QM protein homolog) TRF4-2 16q12.1 topoisomerase-related function protein 4-2 ADCY7 16q12-q13 adenylate cyclase 7 BRD7 16q12 bromodomain containing 7 NKD1 16q12 naked cuticle homolog 1 (Drosophila) SLIC1 16q12.1 selectin ligand interactor cytoplasmic-1 CARD15 16q12 caspase recruitment domain family, member 15 LOC388274 16 LOC388274 CYLD 16q12-q13 cylindromatosis (turban tumor syndrome) SALL1 16q12.1 sal-like 1 (Drosophila) UNGP1 16q12.1 uracil-DNA glycosylase pseudogene 1 LOC388275 16 similar to Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing protein) (Single-strand binding protein) (hnRNP core protein A1) (HDP-1) (Topoisomerase-inhibitor suppressed) LOC388276 16 LOC388276 LOC388277 16 LOC388277
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node   highly
     thymus   highly
    Reproductivefemale systemplacenta  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • twelve transmembrane domains (12TM)
  • 2 guanylate cyclase domains
  • HOMOLOGY
    Homologene
    FAMILY adenylyl cyclase class-4/guanylyl cyclase enzyme family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION adenylate cyclase catalysing the formation of cyclic AMP from ATP and inhibitable by calcium
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    binds 2 magnesium ions per subunit
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS