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FLASH GENE
Symbol ADCY2 contributors: mct/npt - updated : 24-04-2009
HGNC name adenylate cyclase 2 (brain)
HGNC id 233
Location 5p15.31      Physical location : 7.396.342 - 7.830.194
Synonym name
  • ATP pyrophosphate-lyase 2
  • 3',5'-cyclic AMP synthetase
  • rat ATP pyrophosphate lyase homolog
    • Synonym symbol(s) AC2, BAC2, HBAC2, KIAA1060, MGC133314, FLJ16822, FLJ45092
    EC.number 4.6.1.1
    DNA
    TYPE functioning gene
    STRUCTURE 434.00 kb     25 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map pter - D5S1421 - D5S2441 - [D5S1736 - D5S1868 - D5S574 - D5S518 - D5S1957 - D5S208 ] - D5S2088 - D5S1880 - D5S657 - D5S1842 - D5S405 - D5S721 - D5S791 - D5S630 - D5S2046 - D5S23 - D5S1486 - D5S1976 - D5S2095 - D5S759 - D5S1521 - D5S2004 - D5S475 - D5S438E - D5S2480 - D5S2571 - D5S432 - D5S478 - D5S2317 - D5S667 - cen
    Authors Peterson (99)
    Text [ADCY2 ]
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    25 - 6553 - 1091 - Ludwig (2002)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousnerve   highly
    Reproductivefemale systembreastmammary gland  
    Respiratoryrespiratory tracttrachea  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two homologous domain
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • adenyl cyclase class 4/guanylyl cyclase family
    • CATEGORY enzyme , signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • adenylyl cyclase, type II, calmodulin insensitive, may be involved in cAMP biosynthesis, intracellular signaling cascade
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS