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FLASH GENE
Symbol ADCY2 contributors: mct/npt - updated : 24-04-2009
HGNC name adenylate cyclase 2 (brain)
HGNC id 233
Location 5p15.31      Physical location : 7.396.342 - 7.830.194
Synonym name
  • ATP pyrophosphate-lyase 2
  • 3',5'-cyclic AMP synthetase
  • rat ATP pyrophosphate lyase homolog
  • Synonym symbol(s) AC2, BAC2, HBAC2, KIAA1060, MGC133314, FLJ16822, FLJ45092
    EC.number 4.6.1.1
    DNA
    TYPE functioning gene
    STRUCTURE 434.00 kb     25 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map pter - D5S1421 - D5S2441 - [D5S1736 - D5S1868 - D5S574 - D5S518 - D5S1957 - D5S208 ] - D5S2088 - D5S1880 - D5S657 - D5S1842 - D5S405 - D5S721 - D5S791 - D5S630 - D5S2046 - D5S23 - D5S1486 - D5S1976 - D5S2095 - D5S759 - D5S1521 - D5S2004 - D5S475 - D5S438E - D5S2480 - D5S2571 - D5S432 - D5S478 - D5S2317 - D5S667 - cen
    Authors Peterson (99)
    Text [ADCY2 ]
    Physical map
    LOC153297 5p15.33 hypothetical LOC153297 LOC340094 5p15.33 hypothetical protein LOC340094 ADAMTS16 5p15 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16 KIAA0947 5p15.32 KIAA0947 protein MGC5309 5p15.32 hypothetical protein MGC5309 LOC134111 5p15.32 similar to 3110006E14Rik protein LOC389270 5 LOC389270 FLJ20303 5p15.32 hypothetical protein FLJ20303 SRD5A1 5p15.31 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) POLS 5p15 polymerase (DNA directed) sigma LOC391735 5 similar to hypothetical protein FLJ36144 ADCY2 5p15.33-p15.31 adenylate cyclase 2 (brain) MGC5297 5p15.3-p15.2 hypothetical protein MGC5297 MTRR 5p15.31 5-methyltetrahydrofolate-homocysteine methyltransferase reductase SEMA5A 5p15-pter sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A TAS2R1 5p15.2 taste receptor, type 2, member 1 LOC389271 5 LOC389271 LOC134145 5p15.31 hypothetical protein LOC134145 CCT5 5p15.2 chaperonin containing TCP1, subunit 5 (epsilon) LOC134147 5p15.31 hypothetical protein BC001573 TEB4 5p15.2 similar to S. cerevisiae SSM4 ASP 5p15.31 AKAP-associated sperm protein LOC389272 5 LOC389272 LOC389273 5 hypothetical gene supported by AK130861 LOC391736 5 similar to S-antigen precursor - malaria parasite (Plasmodium falciparum) (strain V1/Vietnam) LOC345711 5p15.31 similar to RIKEN cDNA 0610012A05
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    25 - 6553 - 1091 - Ludwig (2002)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousnerve   highly
    Reproductivefemale systembreastmammary gland  
    Respiratoryrespiratory tracttrachea  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two homologous domain
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • adenyl cyclase class 4/guanylyl cyclase family
  • CATEGORY enzyme , signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • adenylyl cyclase, type II, calmodulin insensitive, may be involved in cAMP biosynthesis, intracellular signaling cascade
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS