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Symbol ADAMTS20 contributors: npt/ - updated : 25-09-2003
HGNC name ADAM metallopeptidase with thrombospondin type 1 motif, 20
HGNC id 17178
Location 12q12      Physical location : 43.748.012 - 43.945.724
Synonym name
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 20
  • Synonym symbol(s) GON-1, ADAM-TS20
    EC.number 3.4.24.-
    DNA
    TYPE functioning gene
    STRUCTURE 198.00 kb     39 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    39 - 5733 215 1910 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal, pregnancy
    Text all tissues
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a signal sequence, propeptide, metalloproteinase domain
  • a disintegrin domain
  • a central TS-1 motif
  • a cysteine-rich region
  • a C-terminal TS module
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • may be playing a role in the tissue remodeling process occurring in both normal and pathological conditions
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS