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FLASH GENE
Symbol ACYP2 contributors: - updated : 14-06-2005
HGNC name acylphosphatase 2, muscle type
HGNC id 180
Location 2p16.2      Physical location : 54.342.409 - 54.532.433
Synonym name ACYP
Synonym symbol(s) ACYM, ACYP
EC.number 3.6.1.7
DNA
TYPE functioning gene
STRUCTURE 334.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
CRYGGP1 2q33-q35 crystallin, gamma G pseudogene 1 LOC129656 2p16.3 similar to MECT1 protein LOC388949 2 similar to signal-transducing adaptor protein-2; brk kinase substrate ASB3 2p16-p14 ankyrin repeat and SOCS box-containing 3 XTP3TPB 2p16.3 XTP3-transactivated protein B GPR75 2p16 G protein-coupled receptor 75 PSME4 2p16.1 proteasome (prosome, macropain) activator subunit 4 LOC388950 2 similar to hypothetical protein ACYP2 2p16.2 acylphosphatase 2, muscle type LOC388951 2 similar to Testis-specific Y-encoded-like protein 1 (TSPY-like 1) FLJ40298 2p16.3 hypothetical protein FLJ40298 SPTBN1 2p16 spectrin, beta, non-erythrocytic 1 DKFZp547I014 2p16.3 hypothetical protein DKFZp547I014 RTN4 2p14-p13 reticulon 4 FLJ31438 2p16.3 hypothetical protein FLJ31438 RPS27A 2p16 ribosomal protein S27a MTIF2 2p16-p14 mitochondrial translational initiation factor 2 LOC344405 2p16.3 similar to RIKEN cDNA 2010316F05 LOC55580 2p16.3 hypothetical protein LOC55580 MGC15407 2p16.2 similar to RIKEN cDNA 4931428D14 gene KIAA1387 2p16.2 KIAA1387 protein PNPT1 2p15 polyribonucleotide nucleotidyltransferase 1 EFEMP1 2p16 EGF-containing fibulin-like extracellular matrix protein 1 LOC388952 2 LOC388952 KIAA1912 2p16.2 KIAA1912 protein LOC391374 2 similar to Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 beta subunit) (eIF-2-beta) LOC391375 2 similar to actin
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain   moderately
Reproductivemale systemprostate  moderately
Respiratorylung   moderately
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
secondary structure two beta-sheets
conjugated Other
HOMOLOGY
interspecies ortholog to murine Acyp2
homolog to C.elegans H25K10.2
Homologene
FAMILY acyl phosphatase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION
basic FUNCTION catalyzing the hydrolysis of the carboxyl-phosphate bond of acylphosphates
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism other
signaling
phosphate metabolism
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
induced by tri-iodo-thyronin
repressed by the 5'-untranslated region of its mRNA
Other increased with muscle differentiation
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS