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Symbol ACYP1 contributors: mct/npt - updated : 01-09-2008
HGNC name acylphosphatase 1, erythrocyte (common) type
HGNC id 179
Location 14q24.3      Physical location : 75.519.929 - 75.530.736
Synonym name
  • acylphosphatase, organ-common type isozyme
  • acylphosphate phosphohydrolase 1
  • erythrocyte acylphosphatase 1
    • Synonym symbol(s) ACYPE
    EC.number 3.6.1.7
    DNA
    TYPE functioning gene
    STRUCTURE 10.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 621 - 99 - Heilig (2003)
    - - 700 - 55 - Heilig (2003)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrineneuroendocrinepituitary  highly
     parathyroid   highly
    Hearing/Equilibriumear   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • acylphosphatase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • displays hydrolytic activity on acyl phosphates, nucleoside di- and triphosphates, aryl phosphate monoesters
  • having ability to catalyze phosphotransfer from p-nitrophenyl phosphate to glycerol (but not from benzoyl phosphate to glycerol), as well as the inorganic phosphate-H(2)18O oxygen exchange reaction in the absence of carboxylic acids or phenols
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    phosphate
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS