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FLASH GENE
Symbol ACSM5 contributors: KTN/npt - updated : 04-09-2008
HGNC name acyl-CoA synthetase medium-chain family member 5
HGNC id 26060
Location 16p12.3      Physical location : 20.420.855 - 20.452.278
Synonym name
  • acyl-coenzyme A synthetase ACSM5, mitochondrial
  • Synonym symbol(s) FLJ20581, MACS3
    EC.number 6.2.1.2
    DNA
    TYPE functioning gene
    STRUCTURE 31.40 kb     14 Exon(s)
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    14 - 2428 64 579 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Acsm5 (86.3 pc)
    Homologene
    FAMILY
  • ATP-dependent AMP-binding enzyme family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • acting as a butyrate-CoA ligase
  • having medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro)
  • acting on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
  • fatty acid metabolism
  • lipid metabolic process
  • a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor, nucleotide,
  • Mg2+
  • Mn2+
  • ATP
  • GTP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS