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FLASH GENE
Symbol ACSM1 contributors: - updated : 01-12-2005
HGNC name acyl-CoA synthetase medium-chain family member 1
HGNC id 18049
Location 16p13.1      Physical location : 20.634.558 - 20.702.578
Synonym name
  • butyrate CoA ligase
  • medium-chain acyl-CoA synthase
  • butyryl Coenzyme A synthetase 1
  • Synonym symbol(s) MACS1, BUCS1
    EC.number 6.2.1.2
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster, opposite orientation
    text opposite orientation with SAH
    STRUCTURE 67.00 kb     13 Exon(s)
    MAPPING cloned Y linked N status provisional
    Authors Iwai et al. (03)
    regionally located clustered with other member of the SAH gene family, SAH, MACS2 and MACS3
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver   predominantly
    Urinarykidney   predominantly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Bucs1
    homolog to Drosophila CG13645
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • acts as acyl-coA synthetase for various fatty acids, especially medium-chain fatty acids (MCFA)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS