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FLASH GENE
Symbol ACRV1 contributors: - updated : 02-01-2007
HGNC name acrosomal vesicle protein 1
HGNC id 127
Location 11p12-q13      Physical location : 125.542.229 - 125.550.942
Synonym name sperm protein 10
Synonym symbol(s) SPACA2, D11S4365, SP-10
DNA
TYPE functioning gene
STRUCTURE 8.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter
text structure short 294-bp promoter is capable of conferring developmental stage- and cell type-specific transcription
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1123 28 265 - Wright
- - 1066 - 246 - Wright
- - 958 - 210 - Wright
- - 913 - 195 - Wright
- - 856 - 176 - Wright
- - 838 - 170 - Wright
- - 823 - 165 - Wright
- - 793 - 155 - Wright
lack exon 3
- - 778 - 150 - Wright
- - 691 - 121 - Wright
- - 571 - 81 - Wright
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  specific
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY
CATEGORY structural protein
SUBCELLULAR LOCALIZATION extracellular
text
  • acrosome
  • nascent acrosomal vesicle of golgi phase spermatids
  • basic FUNCTION
  • involved in sperm-zona binding or penetration
  • testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS