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FLASH GENE

Symbol

ACRC

contributors: mct/npt - updated : 30-08-2008

HGNC name	acidic repeat containing
HGNC id	15805

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	Xq13.1      Physical location : 70.797.873 - 70.833.433
Synonym name	putative nuclear protein
Synonym symbol(s)	NAAR1

DNA

TYPE	functioning gene
STRUCTURE	35.00 kb     13 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

regionally located

located in the DYT3 critical region

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ACRC 13 - 2791 76 691 - Nolte (2001)

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine thyroid         Nervous nerve         Reproductive female system breast mammary gland       male system testis

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow       Connective bone       Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a characteristic repeat of 21 units of 8 to 10 amino acids
	several potential nuclear localization signals (NLS) in the C terminus
	putative N glycosylation and phosphorylation sites
	an acidic N terminus and a basic C terminus

HOMOLOGY

interspecies	homolog to Drosophila CG13090
	homolog to C.elegans F42G8.6

Homologene

FAMILY

serine-aspartate repeat-containing protein (SDr) family

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION

playing a role in chromatin structure

CELLULAR PROCESS

nucleotide, chromatin organization, remodeling

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS