Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ACO2 | contributors: mct - updated : 15-03-2013 |
HGNC name | aconitase 2, mitochondrial |
HGNC id | 118 |
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Corresponding disease |
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Location | 22q13.1 Physical location : 41.865.128 - 41.924.992 | ||||
Synonym name | |||||
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Synonym symbol(s) | ACONM, MGC20605, MGC33908, aconitase, mACON | ||||
EC.number | 4.2.1.3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 59.86 kb 18 Exon(s) |
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10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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text | multiple isoforms of the protein (Mirel) |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | MetalloP |
mono polymer | monomer |
HOMOLOGY |
interspecies | ortholog to murine Aco2 |
ortholog to rattus aco2 |
Homologene |
FAMILY | aconitase/IPM isomerase family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION
| intracellular |
intracellular,cytoplasm,organelle,mitochondria,matrix | |
intracellular,nucleus |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
text | iron homeostasis |
PATHWAY |
metabolism | carbohydrate , energetic |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
Other | regulation of mitochondrial aconitase activity by PKC-dependent phosphorylation ![]() |
ASSOCIATED DISORDERS |
corresponding disease(s) | ICRD , OPA9 |
related resource | MITOP database |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |