Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ABRA contributors: - updated : 23-03-2006
HGNC name actin-binding Rho activating protein
HGNC id 30655
Location 8q23.1      Physical location : 107.771.711 - 107.782.472
Synonym name striated muscle activator of Rho-dependent signaling
Synonym symbol(s) FLJ35375, STARS
DNA
TYPE functioning gene
STRUCTURE 9.00 kb     2 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumcardiac  
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Abra
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton
text
  • I-band of the sarcomere
  • actin filaments
  • basic FUNCTION
  • activator of Rho signaling and serum response factor-dependent transcription
  • can activate SRF by inducing the nuclear translocation of the myocardin-related transcription factors MRTFA and MRTFB
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein directly associates with actin
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS