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FLASH GENE
Symbol ABHD3 contributors: - updated : 23-09-2002
HGNC name abhydrolase domain containing 3
HGNC id 18718
Location 18q11.1      Physical location : 19.230.857 - 19.284.766
Synonym name lung alpha/beta hydrolase 3
Synonym symbol(s) LABH3
DNA
TYPE functioning gene
STRUCTURE 53.00 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC342853 18p11.21 similar to KIAA0685 protein LOC388466 18 hypothetical gene supported by NM_032250 LOC284232 18p11.21 similar to Ankyrin repeat domain protein 18A LOC284235 18p11.21 similar to telomeric repeat binding factor 1 isoform 2; Telomeric repeat binding factor 1; telomeric repeat binding protein 1 LOC390834 18 similar to fem-1 homolog a (C.elegans) LOC388467 18 LOC388467 LOC390835 18 hypothetical gene supported by AF124598; NM_001338 LOC388468 18 hypothetical gene supported by BX649118; NM_174981 OR4K7P 18q21.32 olfactory receptor, family 4, subfamily K, member 7 pseudogene LOC390836 18 similar to Olfactory receptor 4K15 LOC341753 18p11.21 similar to Sorting nexin 19 LOC388469 18 similar to breast cancer antigen NY-BR-1.1 LOC390837 18 similar to ENSANGP00000006371 LOC284269 18p11.21 hypothetical gene supported by AK094382 LOC390838 18 hypothetical gene supported by AL832540 LOC388470 18 similar to breast cancer antigen NY-BR-1 ROCK1 18q11.2 Rho-associated, coiled-coil containing protein kinase 1 LOC388471 18 similar to 60S RIBOSOMAL PROTEIN L21 LOC390839 18 similar to Endonuclease G like 1 (Endo G like) FLJ13687 EFO1 18q11.2 establishment factor-like protein SNRPD1 18q11.1 small nuclear ribonucleoprotein D1 polypeptide 16kDa ABHD3 18q11.1 abhydrolase domain containing 3 MIB 18q11.2 ubiquitin ligase mind bomb LOC201484 18q11.2 hypothetical LOC201484 GATA6 18q11.1-q11.2 GATA binding protein 6 CTAGE-1 18p11.2 CTAGE-1 protein CTAGE-2 18p11.2 CTAGE-2 LOC390840 18 similar to ribosomal protein S4, X-linked LOC390841 18 similar to ubiquitin-conjugating enzyme E2C isoform 2; ubiquitin carrier protein E2-C; ubiquitin-protein ligase C; cyclin-selective ubiquitin carrier protein; mitotic-specific ubiquitin-conjugating enzyme RBBP8 18q11.2 retinoblastoma binding protein 8 LOC91768 MGC11386 18q11.2 hypothetical protein MGC11386 RIOK3 18q11.2 RIO kinase 3 (yeast) C18orf8 18q11.2 chromosome 18 open reading frame 8 NPC1 18q11.1-q11.2 Niemann-Pick disease, type C1 LOC147463 18q11.2 hypothetical protein LOC147463 LOC390842 18 similar to 40S ribosomal protein S10 LAMA3 18q11.2 laminin, alpha 3 FLJ33761 18q11.2 hypothetical protein FLJ33761 CABYR 18q11.1 calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) OSBPL1A 18q11-q12 oxysterol binding protein-like 1A IMPACT 18q11.2-q12.1 hypothetical protein IMPACT HRH4 18q11.2 histamine receptor H4 LOC390843 18 similar to hypothetical protein BC005868 LOC342741 18q11.2 similar to DEAD (Asp-Glu-Ala-Asp) box polypeptide 48
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Nervousbrain    
Respiratorylung    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a lung alpha/beta hydolase catalytic triad
HOMOLOGY
interspecies homolog to Drosophila CG10011
homolog to C.elegans T28D6.4
homolog to murine Abhd3
intraspecies homolog to ABHD2
homolog to ABHD1
Homologene
FAMILY alpha/beta hydrolase fold family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION
basic FUNCTION unknown
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS