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FLASH GENE

Symbol

ABCC12

contributors: - updated : 13-04-2005

HGNC name	ATP-binding cassette, sub-family C (CFTR/MRP), member 12
HGNC id	14640

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	16q11-q12      Physical location : 48.116.883 - 48.180.681
Synonym symbol(s)	MRP9

DNA

TYPE	functioning gene
SPECIAL FEATURE	arranged in tandem, opposite orientation
text	tandemly located in tail- to-head orientation with ABCC11
STRUCTURE	63.00 kb     29 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ABCC12 Vc - splicing 5189 - 1009 - Dean ABCC12 Ve - splicing 5168 - 1359 - Dean ABCC12 Vb - splicing 4948 - 935 - Dean ABCC12 Vd5110 - splicing - - 1009 - Dean ABCC12 Va - splicing 5096 - 1009 - Dean

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive female system ovary     lowly   male system testis     lowly   male system prostate     lowly   male system male genital tract seminiferous tubule

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

ortholog to murine Abcc12

Homologene

FAMILY

ATP binding cassette transporter subfamily C (CFTR/MRP)

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

acting as amultispecific organic anion pump which can transport nucleotide

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS