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FLASH GENE
Symbol ABCC12 contributors: - updated : 13-04-2005
HGNC name ATP-binding cassette, sub-family C (CFTR/MRP), member 12
HGNC id 14640
Location 16q11-q12      Physical location : 48.116.883 - 48.180.681
Synonym symbol(s) MRP9
DNA
TYPE functioning gene
SPECIAL FEATURE arranged in tandem, opposite orientation
text tandemly located in tail- to-head orientation with ABCC11
STRUCTURE 63.00 kb     29 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 5189 - 1009 - Dean
- splicing 5168 - 1359 - Dean
- splicing 4948 - 935 - Dean
- splicing - - 1009 - Dean
- splicing 5096 - 1009 - Dean
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemovary  lowly
 male systemtestis  lowly
 male systemprostate  lowly
 male systemmale genital tractseminiferous tubule  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Abcc12
Homologene
FAMILY ATP binding cassette transporter subfamily C (CFTR/MRP)
CATEGORY transport carrier
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • acting as amultispecific organic anion pump which can transport nucleotide
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS