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FLASH GENE
Symbol AADAC contributors: - updated : 08-04-2006
HGNC name arylacetamide deacetylase (esterase)
HGNC id 17
Location 3q21.3-q25.2      Physical location : 151.531.860 - 151.546.277
Synonym symbol(s) DAC
EC.number 2.1.3.5
DNA
TYPE functioning gene
STRUCTURE 14.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map cen - D3S1576 - D3S1309 - D3S1569 - AADAC - D3S1570 - D3S1270 - qter
Authors Yamazaki (97)
Physical map
LOC51122 3q25.1 HSPC042 protein LOC389161 3 hypothetical gene supported by AK027233 LOC389162 3 LOC389162 LOC389163 3 hypothetical gene supported by AK098078 RNF13 3q25.1 ring finger protein 13 PFN2 3q25.1-q25.2 profilin 2 LOC389164 3 similar to Chromosome 1 open reading frame 37 LOC391587 3 similar to peptidyl-Pro cis trans isomerase LOC389165 3 hypothetical gene supported by AF090923; AK023388; BC002719 LOC389166 3 LOC389166 KIAA0669 3q25.1-q25.2 LOC389166 SERP1 3q25.1 stress-associated endoplasmic reticulum protein 1 eIF2A 3q25.1 eukaryotic translation initiation factor (eIF) 2A SELT 3q25.1 selenoprotein T MGC39662 3q25.1 hypothetical protein MGC39662 LOC391588 3 similar to U1 small nuclear ribonucleoprotein C (U1-C) SIAH2 3q25 seven in absentia homolog 2 (Drosophila) LOC389167 3 LOC389167 USH3A 3q21-q25 Usher syndrome 3A TRALPUSH 3q25.1 TRALPUSH H963 3q25.1 TRALPUSH GPR105 3q21-q25 G protein-coupled receptor 105 GPR87 3q24 G protein-coupled receptor 87 GPR86 3q24 G protein-coupled receptor 86 P2RY12 3q24-q25 purinergic receptor P2Y, G-protein coupled, 12 FLJ25972 3q25.1 hypothetical protein FLJ25972 LOC344752 3q25.1 similar to Arylacetamide deacetylase LOC201651 3q25.1 similar to esterase/N-deacetylase (EC 3.5.1.-), 50K hepatic - rabbit AADAC 3q21.3-q25.2 arylacetamide deacetylase (esterase) GPR91 3q24-3q25.1 G protein-coupled receptor 91 MBNL1 3q25.1-q25.2 muscleblind-like (Drosophila) P2RY1 3q25 purinergic receptor P2Y, G-protein coupled, 1 RAP2B 3q25.2 RAP2B, member of RAS oncogene family LOC152118 3q25.2 hypothetical gene supported by AF086445
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveintestinesmall intestine   
 liver    
Endocrineadrenal gland    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
intraspecies homolog to hormone sensitive lipase
Homologene
FAMILY "GDXG" lipolytic enzyme family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
intracellular,cytoplasm,cytosolic,microsome
text type II membrane protein
basic FUNCTION playing an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism amine , drug
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS