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FLASH GENE
Symbol SATB2 contributors: mct/npt/shn/pgu - updated : 06/02/2014
HGNC name SATB homeobox 2
HGNC id 21637
ANIMAL & CELL MODELS
  • loss of Satb2 results in amplification of craniofacial defects and leads both to increased apoptosis in the craniofacial mesenchyme where Satb2 is usually expressed and to changes in the pattern of expression of three genes implicated in the regulation of craniofacial development in humans and mice: Pax9, Alx4, and Msx1 (
  • Satb2-/- embryos have delayed bone formation or mineralization