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FLASH GENE
Symbol WFS1 contributors: mct - updated : 06-11-2018
HGNC name Wolfram syndrome 1 (wolframin)
HGNC id 12762
ANIMAL & CELL MODELS
  • Wfs1-null mouse exhibits progressive insulin deficiency causing diabetes
  • mice with disrupted WFS1 exhibit progressive pancreatic beta cell loss, resulting from the activation of ER stress pathways, delayed cell cycle progression and apoptosis