Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol IRF5 contributors: SGE/npt - updated : 13-07-2018
HGNC name interferon regulatory factor 5
HGNC id 6120
ANIMAL & CELL MODELS
  • Irf5&
  • 8722;/&
    8722; mice show higher susceptibility to viral infection and decreased serum levels of type I IFN and the inflammatory cytokines IL-6 and TNF-alpha (Lien 2010)
  • mice lacking Irf5 accumulate far fewer neutrophils at the site of inflammation due to the reduced levels of chemokines important for neutrophil recruitment, such as the chemokine (C-X-C motif) ligand 1