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FLASH GENE

Symbol

SUPV3L1

contributors: mct/pgu - updated : 02-02-2013

HGNC name	suppressor of var1, 3-like 1 (S. cerevisiae)
HGNC id	11471

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	disruption of the Supv3L1 gene in the mouse has been reported to be embryonic lethal at early developmental stages
	Suv3+/- mice harbored increased mitochondrial DNA (mtDNA) mutations and decreased mtDNA copy numbers, leading to tumor development in various sites and shortened lifespan