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FLASH GENE
Symbol SMS contributors: mct/npt - updated : 25-02-2009
HGNC name spermine synthase
HGNC id 11123
ANIMAL & CELL MODELS
Male gyro (Gy) mice, which have an X chromosomal deletion inactivating the SmS and Phex genes, were found to be profoundly hearing impaired, and showed a striking toxic response to treatment with the ornithine decarboxylase inhibitor alpha-difluoromethylornithine (DFMO) (Wang 2009)