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FLASH GENE

Symbol

NFE2L1

contributors: mct/shn - updated : 07-03-2015

HGNC name	nuclear factor (erythroid-derived 2)-like 1
HGNC id	7781

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	disruption of the transcription factor Nrf-1 results in anemia and embryonic lethality in mice
	mice with somatic inactivation of nrf1 in the liver develop hepatic cancer whose livers exhibit steatosis, apoptosis, necrosis, inflammation, and fibrosis