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FLASH GENE

Symbol

HSPA5

contributors: mct/pgu/shn - updated : 04-06-2019

HGNC name	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HGNC id	5238

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

cytosolic ubiquitin staining is dramatically reduced in GRP78-null Purkinje cells. The mice show retarded growth and severe motor coordination defect by week 5 and cerebellar atrophy by week 13. A novel mouse model of accelerated cerebellar degeneration with basic and clinical applications