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FLASH GENE
Symbol PRKG1 contributors: mct - updated : 30-01-2024
HGNC name protein kinase, cGMP-dependent, type I
HGNC id 9414
ANIMAL & CELL MODELS
  • greater vulnerability to Noise-induced hearing loss (NIHL) in mice with deletion of Prkg1 as compared to mice without the deletion
  • cardiac myocytes from Prkg1R177Q/+ mice showed altered phosphorylation of sarcomeric proteins and reduced contractility in response to electrical stimulation, compared to cells from wild type mice