Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol LMNB1 contributors: mct/npt/pgu - updated : 04-05-2017
HGNC name lamin B1
HGNC id 6637
ANIMAL & CELL MODELS
  • mice that lack a functional Lmnb1 gene die minutes after birth, and fibroblasts from these mice have misshapen nuclei and undergo premature senescence in culture
  • mice expressing nonfarnesylated LmnB1 died soon after birth, with severe neurodevelopmental defects and striking nuclear abnormalities in neurons