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FLASH GENE
Symbol RASD2 contributors: mct/npt - updated : 03-06-2015
HGNC name RASD family, member 2
HGNC id 18229
ANIMAL & CELL MODELS
  • Rhes -/- mice weighed less than wild type mice and displayed minor behavioral abnormalities (Spano 2004)
  • Rhes(-/-) mice showed reduced striatal MTOR signaling and diminished dyskinesia, but maintained motor improvement on L-DOPA treatment
  • Rhes-deleted mice are dramatically protected from neurodegeneration and motor dysfunction in mouse models of Huntington disease