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FLASH GENE
Symbol ZDHHC17 contributors: mct/npt - updated : 23-02-2016
HGNC name zinc finger, DHHC-type containing 17
HGNC id 18412
ANIMAL & CELL MODELS
  • mice deficient for Zdhhc17 expression develop neuropathological and behavioural features similar to HD, and the catalytic activity of Zdhhc13 is impaired in HD mice, most likely due to the reduced interaction of Zdhhc17 with Htt
  • loss of Zdhhc17 and Zdhhc13 leads to early embryonic lethality at day embryonic day 10-11 due to failed chorioallantoic fusion