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FLASH GENE
Symbol SYNE2 contributors: mct - updated : 04-07-2015
HGNC name spectrin repeat containing, nuclear envelope 2
HGNC id 17084
ANIMAL & CELL MODELS
  • mice lacking the actin-binding domain of Nesprin-2 (Nesprin-2DeltaABD), have significant thickening of the epidermis, which is a consequence of the increased epithelial nuclear size
  • Syne-2-/- and Sun1-/- mice exhibit excessive apoptosis in the retina