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FLASH GENE
Symbol ROBO2 contributors: mct/npt/pgu - updated : 05-10-2015
HGNC name roundabout, axon guidance receptor, homolog 2 (Drosophila)
HGNC id 10250
ANIMAL & CELL MODELS
  • in mice lacking robo2, RGC (retinal ganglion cell)axons make qualitatively and quantitatively identical intraretinal pathfinding errors to those reported previously in Slit mutants
  • Slit2 or Robo2 mouse mutants exhibit multilobular kidneys, multiple ureters, and dilatation of the ureter, renal pelvis, and collecting duct system, which lead to vesicoureteral reflux