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FLASH GENE
Symbol KLF5 contributors: mct/pgu - updated : 03-03-2017
HGNC name Kruppel-like factor 5 (intestinal)
HGNC id 6349
ANIMAL & CELL MODELS
  • Klf5 knockout mice, homozygous mutant died before embryonic day 8.5
  • Klf5 +/- mice showed diminished levels of arterial wall thickening angiogenesis, cardiac hypertrophy and intestinal fibrosis in response to external stress
  • Klf5 null mice were markedly deficient in white adipose tissue development