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FLASH GENE
Symbol TOP1MT contributors: mct - updated : 30-11-2015
HGNC name topoisomerase (DNA) I, mitochondrial
HGNC id 29787
ANIMAL & CELL MODELS
  • Top1mt -/- murine embryonic fibroblasts (MEF) exhibit dysfunctional mitochondrial respiration, which leads decreased ATP production and compensation by increased glycolysis and fatty acid oxidation