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FLASH GENE

Symbol

LRAT

contributors: mct - updated : 02-01-2012

HGNC name	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
HGNC id	6685

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	in Lrat&
	8722;/&
	8722; mouse, rod opsin traffics normally to ROS, whereas cone opsins accumulated in inner regions of cones
	in the Lrat-/- model, large quantities of M and S opsins are mislocalized to the inner regions of cones, creating an extra burden on the cell