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FLASH GENE
Symbol POLG contributors: mct/npt - updated : 01- 02-202
HGNC name polymerase (DNA directed), gamma
HGNC id 9179
ANIMAL & CELL MODELS
  • mice expressing proofreading-deficient version of the mitochondrial POLG accumulate mtDNA mutations and display features of accelerated aging
  • in mice a mutation in the catalytic subunit of polymerase gamma (POLG) was associated with haematopoietic dysfunction including anaemia