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FLASH GENE
Symbol NFE2 contributors: mct - updated : 03-10-2016
HGNC name nuclear factor (erythroid-derived 2), 45kDa
HGNC id 7780
ANIMAL & CELL MODELS
  • Nfe2 deficient mice had a significant increase in cortical bone area and cortical thickness, which is consistent with the increase in bone mineral density (BMD) seen only in the Nfe2 deficient femurs
  • mice deficient in Nfe2, transcription factors required for normal megakaryocyte (MK) development, have increased numbers of MKs, reduced numbers of platelets