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FLASH GENE
Symbol MRTFA contributors: mct - updated : 12-04-2018
HGNC name myocardin-related transcription factor A
HGNC id 14334
ANIMAL & CELL MODELS
  • deletion of Mrtf-A in mice attenuates myofibroblast responses following cardiac injury and reduces cardiac fibrosis and scarring
  • defects observed in Mrtf-A/B null mice ranged from reduced cardiac contractility and adult onset heart failure to neonatal lethality accompanied by sarcomere disarray