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FLASH GENE
Symbol ARHGEF1 contributors: mct - updated : 20-05-2010
HGNC name Rho guanine nucleotide exchange factor (GEF) 1
HGNC id 681
ANIMAL & CELL MODELS
  • lungs of Arhgef1-/- mice harbored significantly more leukocytes, increased expression and activity of matrix metalloproteinases (MMPs), airspace enlargement, and decreased lung elastance compared with wild-type lungs