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FLASH GENE
Symbol ABCG5 contributors: mct - updated : 03-11-2015
HGNC name ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1)
HGNC id 13886
ANIMAL & CELL MODELS
  • Abcg5/g8 deficiency in mice fed a chow diet markedly raises TG levels by impairing TG catabolism and by increasing liver and intestinal TG secretion
  • overexpression of ABCG5 and ABCG8 in mice retards diet-induced atherosclerosis because of reduced circulating and hepatic cholesterol