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FLASH GENE
Symbol IL36G contributors: mct - updated : 24-11-2017
HGNC name interleukin 36 gamma
HGNC id 15741
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
is strongly expressed in the aganglionic and ganglionic colon of patients with Hirschsprung disease (HSCR)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • is a valuable biomarker in psoriasis patients, both for diagnostic purposes and measurement of disease activity during the clinical course
  • Therapy target
    SystemTypeDisorderPubmed
    dermatologyskin 
    might provide a future drug target, because of its potential amplifier role in TNF- and IL17 pathways in psoriatic skin inflammation
    ANIMAL & CELL MODELS