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FLASH GENE
Symbol SLCO3A1 contributors: mct - updated : 02-10-2019
HGNC name solute carrier organic anion transporter family, member 3A1
HGNC id 10952
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
SLCO1B3, SLCO2A1, SLC33A1 and SLCO4A1 are up-regulated in pancreatic adenocarcinoma (
tumoral     --low  
in colorectal cancer patients
Susceptibility
  • to alcool and nicotine dependence
  • to intestinal perforation in Crohn disease (CD) patients
  • Variant & Polymorphism other
  • rs207959 (T) allele is a risk allele that alters SLCO3A1 mRNA expression and is associated with intestinal perforation in CD patients
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS