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FLASH GENE
Symbol SIGLEC8 contributors: mct - updated : 07-05-2008
HGNC name sialic acid binding Ig-like lectin 8
HGNC id 10877
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility to asthma
Variant & Polymorphism SNP SNP rs6509541 associated with susceptibility to asthma
Candidate gene
Marker
Therapy target
  • Siglec-8 activation may provide a useful therapeutic approach to reduce numbers of eosinophils (and perhaps basophils and mast cells) in disease states where these cells are important
  • ANIMAL & CELL MODELS