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FLASH GENE
Symbol ATP2C1 contributors: mct - updated : 20-11-2018
HGNC name ATPase, Ca++ transporting, type 2C, member 1
HGNC id 13211
ASSOCIATED DISORDERS
corresponding disease(s) BCPM
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional somatic mutation LOH    
loss of allele in more severely affected segmental skin regions of chronic pemphigus
constitutional       loss of function
renders cells hypersensitive to ER stress
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerreproductivebreast
ATP2C1 modulation and regulation of Golgi calcium transport may provide a unique opportunity for therapeutic targeting of this important pathway in breast cancer
ANIMAL & CELL MODELS