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FLASH GENE
Symbol CLDN10 contributors: mct/npt - updated : 30-09-2016
HGNC name claudin 10
HGNC id 2033
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
of CLDN1 and CLDN10 indicates a favorable prognosis for overall survival in some patients with lung adenocarcinoma
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • in isolated perfused thick ascending limb tubules of claudin-10–deficient mice, paracellular permeability of sodium is decreased, and the relative permeability of calcium and magnesium is increased, and its loss leads to hypermagnesemia and nephrocalcinosis