Symbol
| CLDN10
| contributors: mct/npt - updated : 30-09-2016
|
HGNC name
| claudin 10
|
HGNC id
| 2033
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
of CLDN1 and CLDN10 indicates a favorable prognosis for overall survival in some patients with lung adenocarcinoma | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| in isolated perfused thick ascending limb tubules of claudin-10–deficient mice, paracellular permeability of sodium is decreased, and the relative permeability of calcium and magnesium is increased, and its loss leads to hypermagnesemia and nephrocalcinosis |