Symbol
| CDC37
| contributors: shn/npt - updated : 17-07-2012
|
HGNC name
| CDC37 cell division cycle 37 homolog (S. cerevisiae)
|
HGNC id
| 1735
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
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tumoral
|  
|  
|  
| loss of function
|
loss of CDC37 function induces irreversible growth arrest in androgen receptor-positive and -negative prostate carcinoma cells  | |
Variant & Polymorphism
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Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | | |  |
therapeutic potential of targeting CDC37 in cancer | cancer | reproductive | prostate |  |
essential for maintaining prostate tumor cell growth and may represent a novel target in the search for multitargeted therapies based on the HSP90 chaperone system | neurology | neurodegenerative | alzheimer |  |
new therapeutic targets that could be used to effectively treat neurologic devastating diseases (Alzheimer disease) |
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