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FLASH GENE
Symbol PLA2G7 contributors: mct/npt - updated : 14-06-2008
HGNC name phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
HGNC id 9040
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
  • mutations V279 are a risk factor for stroke in Japanese population
  • suceptibility to atopy and asthma
  • to coronary artery disease
  • Variant & Polymorphism SNP , other
  • I198T
  • A379V protecting against coronary artery disease
  • alleles thr-198 and val-379 are associated with atopy and asthma
  • SNP increasing the risk of coronary artery disease
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS