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FLASH GENE
Symbol CCL27 contributors: mct/npt - updated : 13-01-2010
HGNC name chemokine (C-C motif) ligand 27
HGNC id 10626
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in skin lesions of atopic dermatitis, contact dermatitis and psoriasis
tumoral       gain of function
led to decreased leukocyte recruitment to cutaneous tumor sites and significantly enhanced primary tumor growth (Pivarcsi 2007)
constitutional     --low  
in cutaneous expression during administration of etanercept in psoriasis could be considered a favourable prognostic marker (Campanati 2007)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS