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FLASH GENE
Symbol ITM2B contributors: mct - updated : 10-04-2012
HGNC name integral membrane protein 2B
HGNC id 6174
ASSOCIATED DISORDERS
corresponding disease(s) FBD , FDD
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   LOH    
in prostate tumor (see TSG13A, TSG13B, TSG13D)
constitutional     --low  
specifically decreased in the cerebellum compared to other areas of same brain in MS but not in controls, suggesting that decreased cerebellar ITM2B expression may play a role in cerebellar dysfunction
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS